Industrial work experience
2014-2016 Scientist / manager product development
IQ Products, Groningen, the Netherlands
Key R&D leadership position at a biotech company focused on the development of novel in vitro diagnostics such as immuno assays and flow cytometry tests.
Led research projects and stability studies performed under ISO13485 conditions.
Reviewed scientific literature, resulting in novel research leads.
Initiated and coordinated clinical studies and reported data.
Verified that research activities were compliant with quality standards.
Approved QC results as head QC.
Authored key company patents.
Partnered with QA department for writing and review of quality documents.
2013-2014 Bioprocess engineer
DSM (Patheon) Biologics, Groningen, the Netherlands
Scientific coordination of the manufacture (USP) and purification (DSP) of protein-based pharmaceuticals performed under cGMP conditions.
Prepared cGMP documentation.
Monitored compliance of manufacturing steps with quality standards, together with QA department.
Coordinated collection of QC samples of process intermediates.
Implemented and improved novel (technology transfer) or existing manufacturing processes.
Functioned as primary client contact for production processes.
Academic work experience
2012-2013 Post-doctoral researcher
Department of Biotransformation and Biocatalysis, University of Groningen, the Netherlands.
Developed new enzyme variants for the industrial production of antibiotics in collaboration with DSM Sinochem.
2011-2012 Senior scientist enzymology
Enzyscreen BV, Haarlem, the Netherlands.
Optimized expression and improved activity of biotechnologically relevant enzymes.
2007-2010 Post-doctoral researcher
Department of Molecular Enzymology, University of Groningen, the Netherlands.
Discovered novel redox enzymes and optimized their characteristics to obtain variants for potential industrial applications. This project was performed in collaboration with DSM, Organon and FrieslandCampina.
2002-2007 PhD student
Department of Molecular Microbiology, Vrije Universiteit Amsterdam, the Netherlands.
Elucidated the mechanistic aspects of membrane targeting of bacterial cytoplasmic membrane proteins. Worked successfully as a guest researcher at the Department of Biochemistry and Biophysics, Stockholm University, Sweden during this period.